Top 10 Hyaluronic Acid Suppliers, Manufacturers, Wholesalers, and Traders in Italy

Nestled in the heart of Italy's industrial and financial hub, Lombardy Biotech Solutions has been a cornerstone of the HA industry since 2001. What started as a small lab focused on biopolymer research has grown into a leading manufacturer of high-purity hyaluronic acid, trusted by pharmaceutical giants and supplement brands worldwide. Their claim to fame? A state-of-the-art production facility in Milan that specializes in fermentation-based HA extraction, yielding ultra-pure, low-molecular-weight HA ideal for both oral supplements and injectable medical products.

For businesses in the supplement space, Lombardy Biotech stands out for its customizable HA powders—available in various molecular weights to target specific benefits, from joint health to skin hydration. Their pharmaceutical-grade HA is rigorously tested for heavy metals, (microorganisms), and endotoxins, meeting the strictest EU and FDA standards. But it's not just about quality; they also prioritize scalability. With a production capacity of over 500 tons annually, they can handle large bulk orders without compromising lead times, making them a go-to for enterprise-level clients.

What truly sets Lombardy Biotech apart, though, is their commitment to innovation. Their in-house R&D team regularly collaborates with universities across Europe to develop next-gen HA formulations, including sustained-release supplements and HA conjugates for enhanced stability. If you're looking for a partner that blends reliability with cutting-edge science, this Milan-based manufacturer delivers on both fronts.

When it comes to cosmetic-grade hyaluronic acid, Tuscany Hyaluronics in Florence is a name that resonates with luxury and sustainability. Founded in 1998 by a team of cosmetic chemists, this family-owned business has built its reputation on crafting HA ingredients that feel as good as they work—think silky serums, plumping moisturizers, and gentle skincare raw materials that cater to sensitive skin types. Their flagship product? A fast-absorbing HA serum base that's a favorite among indie beauty brands and high-end labels alike, thanks to its ability to deliver deep hydration without greasiness.

Sustainability is at the core of Tuscany Hyaluronics' ethos. Their production process uses 100% renewable energy, and they source raw materials from local, organic suppliers whenever possible. This commitment has earned them ECOCERT and COSMOS certifications, making their HA extracts a top choice for brands marketing clean, green beauty products. They also offer a "zero-waste" program, where byproducts from HA extraction are repurposed into biodegradable packaging materials—a rare find in the industry.

Beyond serums, Tuscany Hyaluronics wholesales a range of HA-infused ingredients, including hyaluronic acid powder for DIY skincare formulators and pre-mixed gels for small-batch production. Their customer service is another highlight: they provide free sample kits and personalized formulation advice, making them accessible even to new brands just starting out. For anyone in the cosmetic space looking to align with eco-conscious values without sacrificing quality, Tuscany Hyaluronics is a standout choice.

Veneto Pharma Extracts, located in the historic city of Venice, is a heavyweight in the medical-grade hyaluronic acid market. Established in 2005, they've carved a niche as a supplier of HA for injectable treatments, including dermal fillers, ophthalmic surgeries, and joint injections. Their secret? A patented purification process that removes impurities at the molecular level, resulting in HA with exceptional biocompatibility—a critical factor for medical applications where patient safety is paramount.

Medical professionals and pharmaceutical companies trust Veneto Pharma for their EMA-approved HA formulations, which meet the stringent standards of the European Medical Device Regulation (MDR). Their product line includes cross-linked HA gels for long-lasting dermal fillers and linear HA solutions for ophthalmic viscosurgery, each batch tracked via a blockchain system for full traceability. They also offer custom viscosity options, allowing clients to tailor products to specific medical procedures.

But Veneto Pharma isn't limited to medical products. In recent years, they've expanded into oral HA supplements, leveraging their expertise in high-purity extraction to create supplements designed for joint support and skin health. These supplements are formulated with HA of varying molecular weights to optimize absorption, and they're backed by clinical studies conducted in partnership with the University of Padua. For businesses in the medical or nutraceutical sectors seeking HA with uncompromising purity, Veneto Pharma Extracts delivers peace of mind.

For brands prioritizing organic and vegan ingredients, Piedmont Organic HA Co. in Turin is a game-changer. Founded in 2010 by a group of environmental scientists, this innovative supplier specializes in 100% plant-based hyaluronic acid—extracted from fermented corn, not animal sources—making it suitable for vegan, kosher, and halal markets. Their USDA Organic and Vegan Society certifications are a testament to their commitment to ethical sourcing and production.

Piedmont Organic's product range is diverse, with a focus on food-grade and supplement-grade HA. Their organic HA powder is a hit among health food brands, used in everything from vegan protein bars to collagen-boosting smoothies. They also offer ready-to-use supplement capsules, tailored to target joint health (with added glucosamine) or skin hydration (paired with vitamin C). What's unique about their HA? It's fermented using probiotic bacteria, which not only enhances purity but also adds a small amount of beneficial enzymes—making their supplements easier on digestion.

Sustainability is woven into every aspect of their operations. Their Turin facility runs on solar power, and they use water-based extraction methods to minimize waste. They even offer carbon-neutral shipping for all orders, a rarity in the raw materials industry. For brands looking to tap into the growing demand for organic, vegan, and eco-friendly products, Piedmont Organic HA Co. proves that you don't have to sacrifice ethics for quality.

If you're a small-to-medium brand or a wholesaler in need of flexible HA solutions, Emilia-Romagna Wholesale HA in Bologna is your ideal partner. Established in 1995, this family-run wholesaler has built its business on one principle: making high-quality hyaluronic acid accessible to everyone, from startups to regional distributors. They specialize in bulk HA powder (both cosmetic and food-grade), as well as custom formulation services—helping clients create everything from private-label serums to bespoke supplement blends.

What makes them stand out? Their "no minimum order" policy, a rarity in the bulk HA market. Whether you need 1kg of HA powder for a small batch of skincare products or 500kg for a national supplement launch, they're equipped to handle it. They also offer a range of pre-mixed formulations, like HA + niacinamide serums or HA + collagen powder blends, saving clients time and R&D costs. For new brands, their team of formulators provides free consultations, offering advice on ingredient ratios, packaging, and compliance with EU and global regulations.

Emilia-Romagna Wholesale HA also prides itself on transparency. They provide full certificates of analysis (CoA) for every product, detailing molecular weight, purity, and safety test results. Their warehouse in Bologna is strategically located, allowing for fast shipping across Europe—most orders reach clients within 48 hours. For businesses that value flexibility, affordability, and personalized service, this Bologna wholesaler is a reliable choice.

Sicilian Biotech Traders, based in Palermo, is Italy's gateway to global hyaluronic acid markets. Founded in 2012, this trading company specializes in bridging the gap between Italian HA manufacturers and international buyers, with a focus on emerging markets in Africa, South America, and the Middle East. They don't just sell HA—they act as a full-service partner, handling everything from sourcing and quality control to logistics and customs clearance.

What sets Sicilian Biotech Traders apart is their deep network of manufacturing partners across Italy. They work with over 20 HA producers, allowing them to offer a wide range of products: from pharmaceutical-grade injectables to budget-friendly cosmetic serums. This diversity makes them a one-stop shop for buyers with varied needs. For example, a cosmetics brand in Brazil might source organic HA from Tuscany Hyaluronics through Sicilian Traders, while a pharmaceutical company in Nigeria could order medical-grade HA from Veneto Pharma Extracts via the same channel.

They also excel in navigating complex international regulations. Their team includes multilingual experts in global trade, who ensure that products meet local standards—whether it's Nigeria's NAFDAC requirements or Brazil's ANVISA regulations. With offices in Palermo, Dubai, and São Paulo, they provide on-the-ground support for clients in key regions, making cross-border HA sourcing seamless. If you're a global buyer looking to tap into Italy's HA expertise without the hassle of direct manufacturer negotiations, Sicilian Biotech Traders simplifies the process.

Rome's Lazio Cosmetic Ingredients is where science meets luxury in the world of hyaluronic acid. Founded in 2008 by a former skincare chemist from a leading French beauty brand, this supplier focuses on high-performance HA ingredients for premium cosmetics—think anti-aging serums, luxury moisturizers, and high-end facial masks. Their star product? A proprietary "time-release" HA complex that delivers hydration for up to 24 hours, a favorite among luxury brands looking to differentiate their products.

Lazio Cosmetic Ingredients prides itself on innovation. Their R&D lab in Rome has developed HA derivatives like acetylated HA (for better skin penetration) and HA microspheres (for a plumping, immediate effect in serums). They also offer a range of HA-infused raw materials, such as HA powder for creams, HA solution for toners, and even HA-coated exfoliating beads for gentle skincare products. Each ingredient is tested for skin compatibility, with a focus on reducing irritation—making them ideal for sensitive skin lines.

Sustainability and ethics are also key here. They're certified cruelty-free by Leaping Bunny and use recyclable packaging for all shipments. Their production process is water-efficient, and they offset their carbon footprint by investing in reforestation projects in the Italian Alps. For luxury brands that want to combine efficacy, innovation, and sustainability, Lazio Cosmetic Ingredients delivers a premium ingredient experience.

Apulia Health Extracts, based in Bari, is revolutionizing the food and beverage industry with their food-grade hyaluronic acid solutions. Established in 2015, this innovative manufacturer saw a gap in the market for HA that's not just for skincare or supplements but also for functional foods and drinks—and they've filled it with aplomb. Their low-molecular-weight HA powder is specially designed to dissolve easily in liquids, making it perfect for everything from hydration drinks and protein shakes to yogurt and even baked goods.

What makes their HA unique? It's heat-stable and pH-resistant, meaning it retains its properties even in high-temperature processing (like pasteurization) or acidic environments (like fruit juices). This versatility has made them a hit with beverage brands, who use their HA to market drinks as "skin-hydrating" or "joint-supporting." They also offer flavored HA powders—think citrus or berry—for brands looking to add a subtle taste boost to their products without extra sugar.

Apulia Health Extracts is also a leader in clinical research. They've funded studies at the University of Bari that demonstrate the bioavailability of their food-grade HA, showing that oral consumption can increase skin moisture levels and support joint mobility. For food and beverage brands looking to tap into the "beauty from within" trend, this Bari-based manufacturer provides both the ingredients and the scientific backing to make their products stand out.

Campania Pharma Traders, a Naples-based trading company with roots dating back to 1990, is a powerhouse in the global pharmaceutical HA market. They specialize in sourcing and distributing active pharmaceutical ingredients (APIs), including high-purity hyaluronic acid, to drug manufacturers, compounding pharmacies, and medical device companies worldwide. Their strength lies in their ability to navigate the complex regulatory landscape of pharmaceutical trade, ensuring that every product meets the strictest standards—from EDQM certification to WHO GMP compliance.

For pharmaceutical clients, Campania Pharma Traders offers a range of HA APIs, including sodium hyaluronate for injectables and ophthalmic solutions. They also provide semi-finished products, like pre-filled HA syringes for orthopedic use or HA-based eye drops for dry eye treatment. What sets them apart is their global reach: with offices in Naples, Mumbai, and Singapore, they have established relationships with manufacturers across Asia and Europe, allowing them to source cost-effective HA without compromising quality.

They also prioritize reliability in the supply chain. With a network of backup manufacturers, they minimize the risk of delays due to production issues or shipping disruptions—a critical factor in the pharmaceutical industry, where supply chain gaps can impact patient care. For drug companies and medical device manufacturers seeking a trusted partner for HA APIs, Campania Pharma Traders brings decades of experience and a commitment to compliance.

Rounding out our list is Trentino-Alto Adige HA Innovations, a Bolzano-based startup that's redefining sustainability in the HA industry. Founded in 2018, this forward-thinking manufacturer specializes in bio-fermented hyaluronic acid, produced using waste streams from local agriculture—specifically, leftover grape skins and seeds from the region's famous wineries. This circular economy approach not only reduces waste but also creates a uniquely "terroir-driven" HA, with subtle antioxidant properties from the grape byproducts.

Their flagship product is a bio-fermented HA powder with a high molecular weight, ideal for skincare products that require long-lasting hydration. They also offer a "dual-molecular-weight" HA, combining high and low MW HA to target both surface hydration and deep skin penetration. What's exciting for eco-conscious brands is their carbon-neutral certification (ISO 14064) and B Corp status, reflecting their commitment to social and environmental responsibility.

Trentino-Alto Adige HA Innovations is also a hub for collaboration. They partner with startups and research labs to develop sustainable HA applications, from biodegradable HA-based packaging to HA-infused textiles. Their small-batch production model allows for experimentation, making them a favorite among indie beauty brands and sustainable product developers. For businesses looking to align with the growing demand for eco-friendly, innovative ingredients, this Bolzano startup is a trailblazer.