Hyaluronic acid (HA) has become a household name in skincare, supplements, and even pharmaceuticals—and for good reason. This naturally occurring molecule is a hydration powerhouse, capable of holding up to 1000 times its weight in water, making it a cornerstone ingredient for plump, dewy skin and supple joints. Whether you're a small skincare brand crafting the next best hyaluronic acid serum, a supplement company formulating joint health products, or a food manufacturer adding moisture-retaining properties to beverages, the quality of your hyaluronic acid source can make or break your end product.
But with so many suppliers claiming to offer the "best," how do you separate the reliable from the rest? In the U.S., the hyaluronic acid market is thriving, with manufacturers and wholesalers catering to diverse needs—from cosmetic-grade serums to pharmaceutical-grade powders. To help you navigate this landscape, we've curated a list of the top 10 hyaluronic acid suppliers, manufacturers, wholesalers, and traders in the country. Each stands out for its commitment to quality, innovation, and customer trust, ensuring you get the consistency and purity your brand deserves.
1. BioHyaluronic Solutions Inc. (Los Angeles, CA)
Founded in 2005, BioHyaluronic Solutions Inc. has grown from a small lab to one of the most trusted names in hyaluronic acid manufacturing on the West Coast. What sets them apart? Their vertical integration —from sourcing raw materials (they partner with sustainable fermentation facilities in the U.S. and Europe) to producing finished products, they control every step of the process.
Specializing in both high-molecular-weight (HMW) and low-molecular-weight (LMW) hyaluronic acid, they cater to skincare brands (offering serums and moisturizers with proven hyaluronic acid skin benefits), pharmaceutical companies (joint injections and eye drops), and supplement manufacturers (capsules and powders). Their GMP-certified facility in Los Angeles ensures batch-to-batch consistency, and they're proud to be cruelty-free and vegan-friendly.
Customers rave about their custom formulation services —whether you need a specific viscosity for a serum or a powder blend for supplements, their R&D team works closely with clients to deliver tailored solutions. "We've been partnering with BioHyaluronic for three years, and their hyaluronic acid has never let us down," says a senior formulator at a popular clean beauty brand. "Our customers notice the difference in hydration—sales of our HA serum are up 40% since switching."
2. PureHA Labs (Chicago, IL)
For brands prioritizing organic and non-GMO ingredients , PureHA Labs is a top choice. Established in 2010, this Chicago-based manufacturer prides itself on "clean science"—their hyaluronic acid is derived via bio-fermentation using non-GMO corn, free from animal byproducts or harsh chemicals. They're one of the few U.S. suppliers with USDA Organic and Ecocert certifications, making them a favorite among natural skincare and supplement lines.
Their product lineup includes cosmetic-grade HA powders (ideal for serums and masks), food-grade liquid HA (used in beverages and gummies), and pharmaceutical-grade injectables . What customers love most is their transparency: every batch comes with a detailed COA (Certificate of Analysis), and they offer free sample kits so brands can test viscosity, purity, and solubility before committing to bulk orders.
PureHA Labs also leads in sustainability . Their facility runs on 100% renewable energy, and they offset carbon emissions by donating a portion of profits to reforestation projects. "As a brand focused on eco-conscious beauty, partnering with PureHA was a no-brainer," shares the founder of a vegan skincare line. "Their organic hyaluronic acid not only aligns with our values but delivers results—our customers say our moisturizer feels 'like a drink of water for the skin.'"
3. NaturaHyal USA (Houston, TX)
NaturaHyal USA has made a name for itself as the go-to wholesaler for bulk hyaluronic acid , serving small businesses and large corporations alike since 2012. With a warehouse in Houston and distribution centers in New York and Miami, they offer next-day shipping to most U.S. locations, a game-changer for brands with tight production schedules.
Their product range is extensive: from bulk HA powder (1kg to 1000kg orders) to pre-made serum bases (for brands looking to cut down on formulation time). They also stock hyaluronic acid supplements in capsule and powder form, making them a one-stop shop for health and beauty brands. What's unique about NaturaHyal? Their price matching guarantee —they promise to beat any competitor's quote for comparable quality, making them popular with budget-conscious startups.
"We started with a small order of 5kg HA powder from NaturaHyal, and now we're ordering 500kg monthly," says the owner of a growing supplement company. "Their customer service is unmatched—they even helped us troubleshoot a blending issue with our hyaluronic acid and collagen powder. You don't get that with big distributors."
4. Hyaluronic Innovations Group (Boston, MA)
If science-backed innovation is your priority, look no further than Hyaluronic Innovations Group (HIG). Founded by a team of biochemists from MIT, HIG has patents for their proprietary micro-encapsulated HA —a technology that ensures deeper penetration into the skin, enhancing hyaluronic acid skin benefits like long-lasting hydration and reduced fine lines. Their lab in Boston collaborates with dermatologists and universities to test new formulations, making them a leader in cutting-edge HA research.
They specialize in cosmeceutical-grade products , including their popular "Time-Release HA Serum Base," which delivers moisture for up to 12 hours. They also supply pharmaceutical companies with ultra-pure HA for use in ophthalmic surgeries and wound care products. While their prices are higher than some competitors, clients say the investment is worth it: "HIG's micro-encapsulated HA transformed our anti-aging line," notes a skincare brand CEO. "Our customers report visible plumping within 24 hours—repeat purchases are up 60%."
HIG also offers white-label services , allowing brands to slap their logo on HIG's pre-tested formulas. For startups without in-house R&D, this is a shortcut to launching high-quality products quickly.
5. PremiumHA Distributors (Dallas, TX)
PremiumHA Distributors has built its reputation on pharmaceutical-grade quality at wholesale prices. Founded in 2011, they focus exclusively on hyaluronic acid for medical and clinical use, though they also supply high-end cosmetic brands that demand the purest ingredients. Their facility in Dallas is FDA-registered and compliant with USP standards , ensuring their HA meets the strictest purity requirements (99.9% purity, low endotoxin levels).
They offer injectable-grade HA (used in dermal fillers and joint injections), ophthalmic-grade HA (for eye drops and contact lens solutions), and wound-care HA (for dressings and gels). While they don't cater to small orders (minimum 10kg for powders), their bulk pricing is unbeatable for large-scale manufacturers. "As a pharmaceutical company, we can't compromise on quality," says a procurement manager at a leading drugmaker. "PremiumHA's HA has zero contaminants—our lab tests every batch, and they've never failed."
PremiumHA also provides regulatory support , helping clients navigate FDA and EU compliance for new products. For brands expanding internationally, this expertise is invaluable.
6. EcoHyaluronic Industries (Portland, OR)
Oregon-based EcoHyaluronic Industries is on a mission to make hyaluronic acid sustainable and accessible . Since 2012, they've pioneered the use of plant-based fermentation (using organic sugarcane and alfalfa) to produce HA, reducing their carbon footprint by 40% compared to traditional methods. Their facility is LEED-certified, and they use 100% recycled packaging, making them a favorite among eco-conscious brands.
Their product line includes organic HA powder (certified by the Soil Association), biodegradable HA serums (packaged in compostable tubes), and food-grade HA for vegan gummies and beverages. They also offer custom sustainability reports for clients, detailing the environmental impact of their HA purchases—a unique selling point for brands marketing themselves as "green."
"Our customers care about the planet as much as they care about their skin," says the founder of a zero-waste beauty brand. "EcoHyaluronic's HA allows us to say 'sustainable' without greenwashing. Plus, their serum base is so light and absorbent—our customers can't get enough."
7. Science-Backed HA Supplies (Denver, CO)
True to their name, Science-Backed HA Supplies (SBHA) prides itself on data-driven quality . Every batch of their hyaluronic acid undergoes rigorous testing—from molecular weight analysis to microbial counts—and the results are published on their website for full transparency. Founded in 2018 by a team of analytical chemists, SBHA has quickly become a trusted supplier for brands that prioritize third-party validation .
They specialize in research-grade HA (used by universities and labs), cosmetic-grade HA (with detailed viscosity and molecular weight specs), and supplement-grade HA (tested for bioavailability). Their "HA Selector Tool" on their website helps clients choose the right molecular weight for their needs—for example, LMW HA for deep skin penetration or HMW HA for surface hydration.
"As a startup skincare brand, we didn't have the budget for in-house testing," says a formulator. "SBHA's free batch reports gave us the confidence to launch our first HA serum. Now, we use their research-grade HA for our clinical trials—their data is rock-solid."
8. GlobalHA Traders (Atlanta, GA)
For brands sourcing international hyaluronic acid with U.S.-based support, GlobalHA Traders is the bridge between global manufacturers and American businesses. Founded in 2010, they partner with top HA producers in Europe, Asia, and South America, curating a portfolio of high-quality products at competitive prices. Their Atlanta warehouse stocks popular grades, while custom orders from overseas are handled with door-to-door logistics (including customs clearance and documentation).
They offer Korean cosmetic-grade HA (known for its ultra-fine texture), Chinese pharmaceutical-grade HA (cost-effective for bulk orders), and European organic HA (certified by EU standards). What clients appreciate most is their quality control —every international shipment is tested in their in-house lab before being released to customers. "We used to import directly from Asia, but the quality was inconsistent," says a buyer for a national retailer. "GlobalHA vets every supplier, and their lab catches issues before we get the product. It's saved us from costly returns."
GlobalHA also offers forex services , helping clients navigate currency fluctuations when ordering from overseas—a small but crucial detail for budget planning.
9. QualityHA Manufacturing (Phoenix, AZ)
QualityHA Manufacturing is all about simplicity and reliability . Since 2008, this family-owned business in Phoenix has focused on doing one thing exceptionally well: producing consistent, high-quality hyaluronic acid for small to medium-sized brands. They keep their overhead low, passing savings on to customers, and offer no-minimum orders (starting at 100g), making them perfect for startups and hobbyists.
Their core products include cosmetic-grade HA powder , pre-dissolved HA liquid (ready to use in serums), and sample packs (10g to 500g) for testing. They don't offer fancy frills, but their customer loyalty program (10% off after 5 orders) and 24/7 support have built a dedicated following. "I started my skincare line in my kitchen, and QualityHA was there from day one," says a small business owner. "They let me order 100g of HA powder when no one else would, and now I'm a loyal customer. Their HA is just as good as the expensive brands, but without the markup."
10. HerbalHyal USA (Seattle, WA)
Rounding out our list is HerbalHyal USA, a supplier with a focus on natural and herbal-infused HA . Founded in 2015, they combine hyaluronic acid with other botanical extracts (like aloe vera, green tea, and rosehip) to create synergistic blends that boost hyaluronic acid skin benefits. Their Seattle facility is GMP-certified, and they specialize in cosmetic and personal care ingredients .
Popular products include their "HA + Aloe Vera Gel Base" (a hit for after-sun care), "HA + Green Tea Serum Concentrate" (antioxidant-rich for anti-aging), and "HA + Rosehip Oil Emulsion" (for dry skin). They also offer custom herbal blends , working with clients to create unique formulations. "HerbalHyal's blends saved us months of R&D," says a formulator for a natural skincare brand. "Their HA + Green Tea serum base has become our bestseller—customers love that it hydrates and fights free radicals in one step."
| Supplier Name | Location | Key Products | Certifications | Best For |
|---|---|---|---|---|
| BioHyaluronic Solutions Inc. | Los Angeles, CA | HMW/LMW HA, custom formulations | GMP, Cruelty-Free | Skincare, pharmaceuticals, supplements |
| PureHA Labs | Chicago, IL | Organic HA powder, liquid HA | USDA Organic, Ecocert | Natural beauty, vegan supplements |
| NaturaHyal USA | Houston, TX | Bulk HA powder, serum bases, supplements | GMP | Small businesses, fast shipping needs |
| Hyaluronic Innovations Group | Boston, MA | Micro-encapsulated HA, time-release serums | Patented Technology | Science-backed cosmeceuticals |
| PremiumHA Distributors | Dallas, TX | Injectable HA, ophthalmic HA | FDA-Registered, USP | Pharmaceutical, large-scale orders |
| EcoHyaluronic Industries | Portland, OR | Sustainable HA, biodegradable serums | LEED, Organic | Eco-conscious brands |
| Science-Backed HA Supplies | Denver, CO | Research-grade HA, cosmetic HA | Third-Party Tested | Labs, startups needing transparency |
| GlobalHA Traders | Atlanta, GA | International HA (Korean, Chinese, European) | Custom per Supplier | Brands sourcing global ingredients |
| QualityHA Manufacturing | Phoenix, AZ | Small-batch HA powder, pre-dissolved liquid | GMP | Startups, hobbyists, no-minimum orders |
| HerbalHyal USA | Seattle, WA | HA + herbal blends, serum concentrates | GMP | Natural skincare, herbal-infused products |
Choosing the right hyaluronic acid supplier is more than just comparing prices—it's about aligning with your brand's values, quality standards, and production needs. Whether you prioritize sustainability (EcoHyaluronic Industries), scientific innovation (Hyaluronic Innovations Group), or budget-friendly bulk orders (NaturaHyal USA), the suppliers on this list represent the best the U.S. has to offer. Remember to request samples, review batch certificates, and ask about customization options—investing time in vetting your supplier now will save you headaches (and costs) down the line.
As hyaluronic acid continues to dominate skincare, supplements, and beyond, partnering with a reliable supplier isn't just a business decision—it's a commitment to delivering the best for your customers. With this list as your guide, you're one step closer to finding the perfect HA partner for your brand's journey.



