Walk into any skincare aisle or scroll through a health supplement site, and you'll likely see it: hyaluronic acid (HA), the moisture magnet that's taken the beauty and wellness world by storm. Known for its ability to hold up to 1000 times its weight in water, HA is a powerhouse for plump, dewy skin, supple joints, and even hydrated hair. But with so many brands claiming to offer the "best" HA products, how do you separate the hype from the truly exceptional? This list dives into the top 10 hyaluronic acid companies of 2025—brands that have earned trust through innovation, quality, and a genuine commitment to delivering results. Whether you're hunting for the best hyaluronic acid serum for face , seeking hyaluronic acid supplements for joint health, or curious about hyaluronic acid skin benefits , these companies are leading the charge.
| Company Name | Key HA Products | Market Focus | Standout Feature |
|---|---|---|---|
| Bloomage Biotech | Bio-MESO HA Serums, Bulk HA Ingredients | Skincare, Ingredients Supply | Fermentation tech for high-purity HA |
| Shiseido | Benefiance WrinkleResist24 HA Serum | Premium Skincare | Multi-molecular weight HA for deep hydration |
| Nestlé Health Science | Vital Proteins HA Supplements | Supplements, Wellness | Trusted food-grade sourcing and testing |
| Allergan Aesthetics | Juvederm Injections, SkinMedica HA Serums | Medical Aesthetics, Skincare | Bridges clinical and at-home HA care |
| The Ordinary | Hyaluronic Acid 2% + B5 Serum | Affordable Skincare | Transparent, no-frills formulas at low prices |
| SkinCeuticals | H.A. Intensifier Serum | High-Performance Skincare | Boosts skin's natural HA production |
| NOW Foods | HA Capsules, Liquid HA Supplements | Budget Supplements | Third-party tested for purity and safety |
| Rohto Pharmaceutical | Hadalabo Gokujyun HA Moisturizer | Skincare, Eye Care | Gentle formulas for sensitive skin |
| DSM | Biolyn HA (Ingredient) | Ingredients Supply, Nutrition | Sustainable, carbon-neutral HA production |
| L'Occitane en Provence | Immortelle Overnight HA Oil-Serum | Natural Skincare | Organic botanical blends with HA |
1. Bloomage Biotech
If you've ever used a hyaluronic acid product and thought, "This works better than the rest," there's a solid chance Bloomage Biotech played a role. As one of the world's largest HA manufacturers, this Chinese biotech giant doesn't just make consumer products—they supply high-purity HA to brands like L'Oréal, Estée Lauder, and even pharmaceutical companies. What sets them apart? Their proprietary fermentation technology, which produces HA with smaller molecular weights that penetrate deeper into the skin. Their own consumer line, Bio-MESO, has become a cult favorite in Asia, with serums that blend HA with other actives like niacinamide for bright, plump skin. For brands and consumers alike, Bloomage is the gold standard for reliable, effective HA.
2. Shiseido
Shiseido has been a household name in skincare for over 140 years, and their approach to hyaluronic acid is a perfect blend of tradition and innovation. Take their Benefiance WrinkleResist24 HA Serum: it uses three different molecular weights of HA to target surface hydration, deeper skin layers, and long-term moisture retention. Users rave about how it smooths fine lines without feeling heavy, a testament to Shiseido's expertise in texture and formulation. Beyond efficacy, the brand's commitment to sustainability—like using recycled packaging and responsibly sourced ingredients—resonates with eco-conscious shoppers. When you buy Shiseido, you're not just getting a serum; you're investing in a legacy of skincare science.
3. Nestlé Health Science
When it comes to hyaluronic acid supplements, Nestlé Health Science brings the kind of trust that only a global food and wellness leader can. Their Vital Proteins line, acquired a few years back, has become a go-to for HA supplements aimed at joint health and skin radiance. What makes their supplements stand out? They source HA from non-GMO, food-grade origins and subject every batch to rigorous testing for purity. Many users report less joint stiffness after a few weeks of use, and the addition of collagen in some formulations adds an extra boost for skin. For anyone new to HA supplements, Nestlé's approachable branding and clear dosage instructions make it easy to start—no guesswork required.
4. Allergan Aesthetics
Allergan Aesthetics is a name synonymous with medical-grade HA, thanks to Juvederm, the dermal filler used by dermatologists worldwide to plump lips and smooth wrinkles. But in recent years, they've expanded into at-home care with lines like SkinMedica, making their clinical expertise accessible to everyone. Their SkinMedica HA5 Rejuvenating Hydrator is a standout: it combines five forms of HA to mimic the skin's natural moisture barrier, delivering all-day hydration. What's cool is how Allergan bridges the gap between in-office treatments and daily skincare—many dermatologists recommend their serums to patients post-procedure to extend results. For those who want the best of medical and consumer HA care, Allergan delivers.
5. The Ordinary
The Ordinary revolutionized skincare by proving that effective ingredients don't have to cost a fortune, and their Hyaluronic Acid 2% + B5 Serum is a prime example. Priced under $10, this serum skips fancy packaging and marketing to focus on what matters: pure HA (2%) and vitamin B5 to enhance moisture retention. Users love its simplicity—no fragrances, no parabens, just a lightweight gel that absorbs quickly and works under makeup. The brand's transparency is another win: they list every ingredient and explain how it works, empowering consumers to make informed choices. Whether you're a skincare newbie or a veteran, The Ordinary's HA serum is a reminder that great skincare can be accessible to all.
6. SkinCeuticals
If you're willing to splurge on a best hyaluronic acid serum , SkinCeuticals' H.A. Intensifier is often called "life-changing" by skincare enthusiasts. What makes it worth the higher price tag? Unlike most HA serums that just add moisture, this one boosts the skin's own ability to produce HA, leading to longer-lasting results. It also contains proxylane and licorice root extract to support collagen and reduce redness. Many users notice plumper, more radiant skin within a month, and dermatologists frequently recommend it for mature skin or those dealing with dryness from retinol use. Yes, it's an investment, but for anyone serious about anti-aging, it's hard to beat.
7. NOW Foods
NOW Foods has been a staple in health food stores for decades, and their hyaluronic acid supplements are a budget-friendly option without sacrificing quality. Their HA capsules contain 100mg of HA per serving, sourced from fermented bacteria (a vegan-friendly choice), and they're free from common allergens like gluten and soy. What's great about NOW is their commitment to affordability—you can get a month's supply for under $20, making HA supplements accessible to students, parents, and anyone on a tight budget. They also offer liquid HA for those who prefer not to swallow pills, with a mild citrus flavor that's easy to mix into water or smoothies. For no-nonsense, reliable supplements, NOW Foods delivers.
8. Rohto Pharmaceutical
Rohto, a Japanese brand known for their cooling eye drops, has quietly become a favorite for gentle, effective HA skincare. Their Hadalabo Gokujyun line, popular in Asia and now available globally, focuses on simplicity: just pure HA and a few supporting ingredients. The Gokujyun Premium HA Lotion is a hit among those with sensitive skin—it's fragrance-free, alcohol-free, and absorbs in seconds, leaving skin dewy but not greasy. Rohto's approach to HA is all about hydration without irritation, making it ideal for acne-prone or rosacea-prone skin types. Plus, the affordable price point (under $20 for a large bottle) means you can slather it on morning and night without guilt.
9. DSM
DSM might not be a household name, but chances are, your favorite HA product contains their ingredients. As a global leader in nutrition and health, DSM supplies high-quality HA to brands across skincare, supplements, and even pharmaceuticals. Their Biolyn HA is prized for its purity and consistency, made using sustainable fermentation processes that reduce environmental impact. What's impressive is DSM's focus on research—they fund studies on HA's benefits beyond hydration, like its role in wound healing and gut health. For brands, partnering with DSM means access to cutting-edge HA science; for consumers, it means products you can trust to deliver on their promises.
10. L'Occitane en Provence
L'Occitane brings a touch of French luxury to hyaluronic acid with their Immortelle Overnight Reset Oil-in-Serum. Blending HA with organic immortelle flower oil and shea butter, this product hydrates while also repairing skin overnight. Users love the rich, nourishing texture—perfect for dry winter months—and the subtle, herbal scent that makes skincare feel like a spa ritual. What sets L'Occitane apart is their use of organic, locally sourced ingredients from Provence, supporting small-scale farmers and reducing their carbon footprint. For those who want hyaluronic acid skin benefits with a side of sustainability and luxury, this brand delivers in spades.
Hyaluronic acid has become a staple in modern beauty and wellness, and these 10 companies are leading the way in making it more effective, accessible, and innovative than ever. Whether you're reaching for a best hyaluronic acid serum to boost your skincare routine, trying hyaluronic acid supplements for joint health, or exploring the many hyaluronic acid skin benefits , the key is to choose brands that prioritize quality, transparency, and your unique needs. After all, the best HA product isn't just about the ingredient—it's about the trust you feel in the company behind it. Here's to healthier, happier skin (and joints!) in 2025 and beyond.



