1. Panama Natural Extracts Co.
Founded in 2005 and based in Panama City's industrial zone, Panama Natural Extracts Co. has established itself as a leading milk thistle extract manufacturer in Central America. What sets them apart is their vertically integrated approach: from sourcing raw milk thistle seeds (sourced from sustainable farms in Ecuador and Colombia) to in-house extraction and packaging, they control every step of the process. This ensures consistency and quality, making them a favorite among pharmaceutical companies and large-scale supplement brands.
Specializing in bulk milk thistle extract, they offer both powder and liquid forms, with silymarin concentrations ranging from 80% to 95%. Their facility is GMP-certified and compliant with ISO 9001 standards, and they provide detailed COA (Certificate of Analysis) and MSDS reports for every batch. While their minimum order quantity (MOQ) starts at 500kg for bulk orders, they also cater to smaller businesses with flexible pricing for repeat clients. Recent expansions have allowed them to serve clients across Latin America, the Caribbean, and even Europe, with shipping from the Colon Free Zone ensuring fast delivery times.
2. Silymarin Solutions Panama
For businesses prioritizing organic and high-purity extracts, Silymarin Solutions Panama is a standout milk thistle extract supplier . Established in 2012 in David, Chiriquí, this family-owned company has built its reputation on sourcing organic milk thistle seeds from certified farms in Costa Rica and processing them using cold-press extraction methods to preserve silymarin's potency. Their focus on sustainability extends to their packaging—using recyclable materials—and their commitment to fair trade practices with farmers.
While they don't manufacture in-house, they partner with GMP-certified extractors in Panama and Colombia to produce extracts tailored to client needs, including organic-certified options (USDA and EU organic compliant). Their product line includes standard milk thistle extract (70-80% silymarin), as well as specialized formulations like water-soluble extracts for beverages and cosmetic-grade extracts for skincare products. As a supplier, they excel in customer service, offering personalized consultations to help clients choose the right extract for their industry—whether it's a small herbal supplement brand or a multinational cosmetic company. MOQs start at 100kg, with discounts for annual contracts.
3. Tropical Bulk Botanicals
Located in the Colon Free Zone, Tropical Bulk Botanicals is a go-to wholesaler for businesses needing large quantities of milk thistle extract at competitive prices. Founded in 2010, they specialize in bulk distribution, sourcing extracts from manufacturers across Latin America and Asia and repackaging them for regional clients. Their strength lies in their logistics network: the Colon Free Zone's tax-free status and proximity to major shipping routes (Panama Canal) allow them to offer fast delivery times—often within 3-5 business days for local Panama clients and 7-10 days for regional orders.
Tropical Bulk Botanicals offers a range of milk thistle extract products, including standard powder (80% silymarin), micronized powder for easier blending, and liquid extracts for tinctures. They work with both high quality milk thistle extract manufacturers (ensuring all products meet USP and EP standards) and budget-friendly options for price-sensitive buyers, making them versatile for businesses of all sizes. Their MOQ is 1,000kg for bulk orders, but they also provide "sample packs" (1kg-10kg) for businesses looking to test quality before committing to large purchases. With a dedicated sales team fluent in Spanish, English, and Portuguese, they've become a trusted partner for wholesalers and distributors across Brazil, Mexico, and the Caribbean.
4. Panama Pharma Extracts
Catering specifically to the pharmaceutical and nutraceutical industries, Panama Pharma Extracts is a manufacturer with a focus on precision and compliance. Established in 2018 in Panama City's biomedical park, their state-of-the-art facility is equipped with advanced extraction technology (supercritical CO2 extraction) and an in-house lab for rigorous testing—including HPLC analysis to verify silymarin content and microbial testing to ensure purity. This attention to detail has earned them certifications like ISO 13485 (medical device quality management) and cGMP, making them a preferred supplier for companies producing prescription liver supplements and clinical-grade products.
Their product line is narrow but specialized: they offer pharmaceutical-grade milk thistle extract with silymarin concentrations up to 98%, as well as custom formulations for controlled-release supplements. Unlike many suppliers, they also provide R&D support, helping clients develop new products or optimize existing ones. While their pricing is higher than general wholesalers, the quality and compliance support justify the cost for businesses in regulated industries. MOQs start at 250kg, and they offer long-term supply contracts with fixed pricing to help clients manage costs. With a focus on innovation, they recently introduced a nano-encapsulated milk thistle extract, designed to enhance bioavailability—a game-changer for pharmaceutical applications.
5. Green Leaf Traders Panama
As a trader , Green Leaf Traders Panama acts as a bridge between global milk thistle extract manufacturers and local businesses in Panama and Latin America. Founded in 2015, they don't produce extracts themselves but have built an extensive network of partners—including manufacturers in China, India, and Europe—that allows them to offer a wide range of products at competitive prices. Their niche is flexibility: whether you need a small batch of organic extract for a boutique skincare line or a large order of bulk powder for animal feed supplements, they can source it.
What makes Green Leaf Traders valuable is their expertise in navigating international trade regulations. They handle all import/export documentation, including customs clearance through the Colon Free Zone, and offer door-to-door delivery across Panama. Their product catalog includes standard milk thistle extract, organic options, and even specialized variants like deodorized extract (ideal for food and beverage applications where taste is a concern). They also provide third-party lab testing upon request, giving clients peace of mind about quality. MOQs are as low as 50kg for most products, and they pride themselves on transparency—providing full traceability reports for every shipment, including origin of raw materials and extraction methods. For businesses new to sourcing botanical extracts, their team offers free consultations to help assess needs and budget.
6. Organic Thistle Extracts
True to its name, Organic Thistle Extracts is a milk thistle extract supplier that specializes in organic and sustainably sourced products. Based in Boquete, a region known for its fertile soil and eco-friendly farming practices, the company was founded in 2010 by a group of herbalists and agronomists passionate about clean, plant-based ingredients. They source milk thistle seeds from small-scale organic farms in Panama's Chiriquí Highlands, ensuring fair wages for farmers and minimizing environmental impact through crop rotation and natural pest control.
Their extraction process uses only purified water and ethanol (no harsh chemicals), resulting in extracts that are ideal for natural skincare and organic supplements. They offer two main products: organic milk thistle extract powder (80% silymarin, USDA certified) and liquid extract (tincture form, 1:5 ratio). Both are tested for heavy metals, pesticides, and microbial contamination, with results available on request. While their focus is on organic products, they also offer conventional extracts for clients with budget constraints. As a small-batch supplier, they prioritize quality over quantity, with MOQs starting at 25kg for powders and 50 liters for liquids. They've built a loyal following among natural product brands in Panama and Costa Rica, thanks to their commitment to education—hosting workshops on the milk thistle extract benefits and sustainable sourcing practices.
7. Bulk Botanicals Panama
Bulk Botanicals Panama, located in the Tocumen Free Zone, is a wholesaler that lives up to its name—focused solely on providing bulk milk thistle extract to businesses across Latin America. Founded in 2012, they've carved out a niche by offering high-volume orders at some of the lowest prices in the region, making them a top choice for manufacturers of animal supplements, functional foods, and budget-friendly herbal products. Their secret? Direct partnerships with large-scale extract manufacturers in India and China, which allows them to bypass middlemen and pass savings to clients.
They offer standard milk thistle extract powder (70-80% silymarin) in bulk quantities, with MOQs starting at 1,000kg (though they can accommodate smaller orders of 500kg for repeat clients). While they don't specialize in organic or pharmaceutical-grade products, their extracts meet food-grade standards and are tested for basic quality parameters (silymarin content, moisture, ash). What they lack in frills, they make up for in reliability: they maintain large stockpiles in their Tocumen warehouse, ensuring same-day or next-day shipping for orders within Panama. For businesses outside Panama, they offer competitive freight rates through partnerships with major shipping lines, with delivery times to Mexico, Colombia, and Brazil averaging 5-7 days. Their customer service team is available 24/7 to handle urgent orders, and they offer discounts for annual contracts, making them a favorite among high-volume buyers.
8. Panama Botanical Labs
Panama Botanical Labs, founded in 2018, is a milk thistle extract manufacturer with a focus on innovation and high-purity extracts. Based in Panama City's biotechnology park, their facility is equipped with cutting-edge extraction equipment, including ultrasonic and microwave-assisted extraction technologies, which allow them to produce extracts with higher silymarin yields and better solubility than traditional methods. This makes their products ideal for advanced applications like nanomedicine, nutraceuticals, and high-end skincare.
They specialize in custom formulations, working closely with clients to develop extracts tailored to specific needs—whether it's a water-soluble powder for energy drinks or a liposomal liquid extract for enhanced absorption in supplements. Their standard product line includes ultra-high-purity milk thistle extract (95-98% silymarin), as well as standardized extracts with specific ratios of silybin (the most active component of silymarin). All products are tested in their in-house lab using HPLC and UV-Vis spectroscopy, with COA reports provided for every batch. While their pricing is premium, their technical support sets them apart: their team of chemists and biologists offers free consultations to help clients optimize formulations and troubleshoot issues. MOQs start at 100kg for standard products and 250kg for custom formulations. They also collaborate with universities in Panama on research projects, staying at the forefront of milk thistle extract innovation.
9. Latin American Extract Traders
Latin American Extract Traders (LAET) is a regional trader with a focus on connecting Panama-based businesses to the broader Latin American market. Founded in 2013, they have offices in Panama City, Mexico City, and São Paulo, allowing them to coordinate sourcing, distribution, and logistics across the continent. Their strength is their deep understanding of local markets—whether you're a Panamanian supplement brand looking to export to Brazil or a Colombian pharmaceutical company needing to import milk thistle extract, LAET handles the complexities of cross-border trade.
They work with a curated list of milk thistle extract manufacturers in Panama, Argentina, and Spain, ensuring a steady supply of high-quality extracts. Their product range includes conventional and organic options, with silymarin concentrations from 70% to 90%. They also offer value-added services like private labeling, packaging, and regulatory compliance support (helping clients navigate local health authorities like Panama's Ministry of Health or Brazil's ANVISA). MOQs are flexible, starting at 50kg for local orders and 200kg for exports. What clients appreciate most is their reliability: they guarantee on-time delivery and offer a satisfaction guarantee, with returns accepted if products don't meet specifications. For businesses looking to expand regionally, LAET's network and market knowledge make them an invaluable partner.
10. Pure Silymarin Panama
Pure Silymarin Panama rounds out our list as a specialized milk thistle extract supplier focused exclusively on silymarin—the active compound in milk thistle. Founded in 2015 by a team of pharmacists, the company sources raw milk thistle seeds from premium farms in Chile and uses a proprietary extraction process to isolate silymarin, resulting in highly concentrated powders and liquids. This specialization makes them a top choice for businesses that need pure silymarin for research, pharmaceutical development, or high-potency supplements.
They offer silymarin in various forms: standard powder (90-95% purity), micronized powder (for better dissolution), and crystalline silybin (98% purity, for pharmaceutical use). All products are tested for identity, purity, and potency using HPLC and NMR spectroscopy, with strict adherence to USP and EP monographs. While they don't offer full-spectrum milk thistle extract, their pure silymarin is ideal for clients who want to control the concentration in their formulations. MOQs start at 10kg for standard powders and 1kg for high-purity silybin, making them accessible to small research labs and large pharmaceutical companies alike. They also provide technical data sheets and research support, including references to clinical studies on silymarin's benefits. With a focus on quality and specialization, Pure Silymarin Panama has become a trusted partner for businesses at the cutting edge of milk thistle extract applications.
| Company Name | Type | Specialty | Certifications | Minimum Order Quantity (MOQ) | Key Products |
|---|---|---|---|---|---|
| Panama Natural Extracts Co. | Manufacturer | Vertical integration, bulk production | GMP, ISO 9001 | 500kg | Pharmaceutical-grade powder (80-95% silymarin) |
| Silymarin Solutions Panama | Supplier | Organic, cosmetic/pharmaceutical | USDA/EU Organic | 100kg | Organic powder, water-soluble extract |
| Tropical Bulk Botanicals | Wholesaler | Bulk quantities, fast delivery | USP/EP compliant | 1,000kg (500kg repeat) | Bulk powder, micronized powder, liquid extract |
| Panama Pharma Extracts | Manufacturer | Pharmaceutical-grade, custom formulations | ISO 13485, cGMP | 250kg | 98% silymarin powder, nano-encapsulated extract |
| Green Leaf Traders Panama | Trader | Global sourcing, flexibility | Varies by manufacturer | 50kg | Organic, conventional, deodorized extract |
| Organic Thistle Extracts | Supplier | Organic, small-batch | USDA Organic | 25kg | Organic powder, liquid tincture |
| Bulk Botanicals Panama | Wholesaler | High-volume, low-cost | Food-grade | 1,000kg | Standard bulk powder (70-80% silymarin) |
| Panama Botanical Labs | Manufacturer | Innovation, custom formulations | GMP, ISO 17025 (lab) | 100kg (standard), 250kg (custom) | Ultra-high-purity powder, water-soluble extract |
| Latin American Extract Traders | Trader | Regional distribution, regulatory support | Varies by manufacturer | 50kg (local), 200kg (export) | Conventional/organic powder, private labeling |
| Pure Silymarin Panama | Supplier | Pure silymarin, research/pharma | USP, EP compliant | 10kg (standard), 1kg (high-purity) | 90-98% silymarin powder, crystalline silybin |



