Top 10 Silymarin Suppliers, Manufacturers, Wholesalers, and Traders in Spain

Founded in 2005 in Valencia, GreenHarvest Botanicals has grown from a small family-run operation to one of Spain's leading manufacturers of botanical extracts, with silymarin as its flagship product. What sets them apart? A vertically integrated supply chain that starts with partnering with local Spanish farmers to source organic milk thistle seeds, ensuring full traceability from farm to final product. Their state-of-the-art extraction facility in Alicante uses cold-press technology to preserve silymarin's potency, resulting in extracts with purity levels ranging from 70% to 95%—a favorite among pharmaceutical and supplement brands.

GreenHarvest prides itself on sustainability: their production process is energy-efficient, and they recycle water used in extraction. They hold GMP, ISO 9001, and organic certifications (EU Organic, USDA Organic), making them a go-to for brands prioritizing eco-friendly and certified ingredients. With a production capacity of 500 metric tons of silymarin annually, they cater to both small-batch orders (starting at 10 kg) and large-scale bulk needs, serving clients across Europe, North America, and Asia.

If you're a small to medium-sized business looking for flexible wholesale options, Iberian Extracts Wholesale in Madrid should be on your radar. Established in 2010, this wholesaler specializes in bridging the gap between manufacturers and end-users, offering a curated range of botanical extracts—including high-quality silymarin—at competitive prices. They work directly with 12 local manufacturers (including some on this list) to ensure a steady supply, and their focus on customer service means they're happy to customize orders to fit specific purity or packaging needs.

Iberian Extracts doesn't just stop at silymarin; their catalog includes over 200 botanical extracts, making them a one-stop shop for brands looking to diversify their product lines. They offer fast turnaround times (typically 3–5 business days for EU orders) and minimum order quantities as low as 5 kg, which is a boon for startups. While they don't produce in-house, their rigorous quality control team tests every batch for heavy metals, pesticides, and purity, ensuring consistency across all products.

Based in Barcelona, Mediterranean Botanicals has made a name for itself as a global exporter of premium silymarin, with a focus on high-purity extracts for the pharmaceutical industry. Founded in 1998, they have over two decades of experience perfecting their extraction process, which combines traditional methods with modern technology to achieve silymarin concentrations of up to 98%. Their facility is GMP and ISO 13485 certified (a rare feat for botanical extract manufacturers), meaning their products meet the strict standards required for use in pharmaceuticals.

What truly distinguishes Mediterranean Botanicals is their commitment to research and development. They collaborate with universities across Spain to study silymarin's potential applications, from liver support to anti-aging skincare. They also offer custom formulations, working with clients to develop silymarin blends tailored to specific needs—whether it's a slow-release supplement or a water-soluble extract for beverages. With a global reach spanning over 40 countries, they're a trusted partner for international brands seeking reliability and innovation.

For brands prioritizing organic and sustainably sourced ingredients, EcoNatura Traders in Seville is a standout choice. As a certified organic trader, they specialize in connecting European buyers with organic silymarin from Spain's certified organic farms. Unlike manufacturers, they don't produce extracts themselves but curate a selection of the finest organic silymarin, ensuring every batch is certified by EU Organic, Ecocert, and Demeter (for biodynamic options).

EcoNatura's strength lies in their network of small-scale farmers in Andalusia, where milk thistle is grown without synthetic pesticides or fertilizers. This focus on sustainability extends to their packaging—they use 100% recyclable materials and offset carbon emissions from shipping. While their prices are slightly higher than non-organic options, the quality and ethical sourcing make them a favorite among premium supplement and skincare brands. They also offer educational resources for clients, including sustainability reports and farmer profiles, helping brands tell a compelling story to their customers.

Located in Zaragoza, BioExtract Solutions is a versatile player that wears two hats: manufacturer of standard silymarin extracts and contract manufacturer for brands looking to outsource production. Since 2012, they've built a reputation for flexibility, offering everything from bulk raw silymarin powder to finished capsules and liquid extracts. Their 10,000-square-meter facility includes a dedicated contract manufacturing wing, where they can handle everything from formulation development to packaging, making them ideal for brands without in-house production capabilities.

BioExtract's silymarin line includes both conventional and organic options, with purity levels from 50% to 90%. They're also known for their quick turnaround on custom orders—if you need a specific particle size or solubility profile, their R&D team can deliver in as little as two weeks. With certifications including ISO 22000 (food safety) and Kosher, they cater to a wide range of industries, from food and beverages to cosmetics.

When it comes to sheer scale, Iberia Bulk Exports in Bilbao is hard to beat. As one of Spain's largest wholesalers of botanical extracts, they specialize in bulk silymarin (think 1-tonne orders and above) for industrial clients, including multinational supplement companies and food manufacturers. Founded in 1995, they've built a massive distribution network that allows them to offer competitive prices—thanks to economies of scale—and reliable delivery to ports across Europe, Asia, and the Americas.

While they don't focus on small orders, Iberia Bulk Exports makes up for it with consistency and efficiency. Their warehouse in Bilbao stocks over 500 tonnes of silymarin at any given time, ensuring fast shipping even for large quantities. They also offer flexible payment terms for repeat clients, making them a popular choice for businesses with ongoing needs. Their silymarin is sourced from a network of Spanish manufacturers, and they conduct third-party testing on every batch to ensure it meets international standards for heavy metals and microbial contamination.

For pharmaceutical companies and high-end supplement brands, PureHerb Pharma in Madrid is a top pick. Specializing exclusively in pharmaceutical-grade silymarin, they adhere to the strictest quality standards, with their facility meeting EU GMP Annex 1 (for sterile products) and FDA guidelines. Founded in 2008, they've invested heavily in advanced testing equipment, including HPLC and GC-MS, to ensure their silymarin is free from impurities and has consistent potency batch after batch.

PureHerb's silymarin is available in various forms, including micronized powder (for better absorption) and standardized extracts with specific ratios of silybin (the most active component of silymarin). They also offer documentation to support regulatory submissions, including Certificates of Analysis (CoA), Material Safety Data Sheets (MSDS), and stability studies—critical for pharmaceutical clients navigating strict approval processes. While they primarily serve the pharmaceutical industry, they also work with ｓｅｌｅｃｔ supplement brands that prioritize pharmaceutical-grade ingredients.

For businesses based in Spain or Southern Europe, Andalusian Botanicals offers a hyper-local option with a personal touch. Based in Granada, this wholesaler is part of a cooperative of 30+ small-scale farmers in Andalusia who grow milk thistle and other herbs. By cutting out the middleman, they're able to offer fresh, locally sourced silymarin at competitive prices, with a focus on supporting the regional agricultural community.

Andalusian Botanicals prides itself on transparency: clients can visit the farms where their milk thistle is grown, and they provide detailed harvest reports and soil analyses upon request. Their silymarin is available in both conventional and organic varieties, with purity levels up to 80%. While their delivery range is primarily limited to Spain and Southern France, they make up for it with personalized service—many clients rave about their responsive customer support and willingness to accommodate small, last-minute orders.

As the name suggests, Global Extracts Trading in Barcelona is all about connecting Spain's silymarin to the world. Founded in 2010, this trader specializes in exporting Spanish silymarin to markets like North America, Asia, and the Middle East, where demand for European-quality botanical extracts is high. They work with a ｓｅｌｅｃｔ group of Spanish manufacturers (including GreenHarvest and Mediterranean Botanicals) to ensure a consistent supply of high-quality silymarin, and their in-depth knowledge of international regulations (like the FDA's NDI process or China's CFDA requirements) makes them invaluable for brands expanding globally.

Global Extracts Trading also offers logistics support, handling everything from customs clearance to shipping insurance, taking the hassle out of international trade. They're particularly strong in Asia, where they've built relationships with distributors in China, Japan, and South Korea. While they don't produce their own extracts, their expertise in global markets and commitment to compliance make them a trusted partner for brands looking to go beyond Europe.

Rounding out our list is Naturaleza Pura, a manufacturer in Malaga that's leading the way in sustainable silymarin production. Founded in 2015 by a team of environmental scientists, the company has made sustainability its core mission, from using renewable energy in its extraction facility (solar panels power 80% of operations) to recycling 100% of waste materials from the extraction process (the leftover milk thistle pulp is turned into animal feed).

Their silymarin is certified by the Rainforest Alliance and the Sustainable Food Lab, making them a top choice for brands with strong sustainability values. But sustainability doesn't come at the cost of quality: their extracts have purity levels up to 85% and are popular in eco-friendly supplements and natural skincare lines. They also offer a "zero-waste" bulk option, where extracts are shipped in reusable containers that are returned and sanitized, further reducing environmental impact. With a focus on innovation and planet-friendly practices, Naturaleza Pura is a glimpse into the future of botanical extract production.